A Dyslexia-Associated Variant in DCDC2 Changes Gene Expression

2010/11/02 by Haiying Meng, Natalie R. Powers, Ling Tang +8 · 24 citations
Biochemistry, Genetics and Molecular Biology · #Genetics and Neurodevelopmental Disorders #Ubiquitin and proteasome pathways #RNA modifications and cancer

paper · doi:10.1007/s10519-010-9408-3

Cited by

• Moving closer to a public health model of language and learning disabilities: the role of genetics and the search for etiologies. [europepmc]
• Dcdc2 knockout mice display exacerbated developmental disruptions following knockdown of doublecortin. [europepmc]
• DCDC2 genetic variants and susceptibility to developmental dyslexia. [europepmc]
• Approach to epigenetic analysis in language disorders. [europepmc]
• Variants in the DYX2 locus are associated with altered brain activation in reading-related brain regions in subjects with reading disability. [europepmc]
• The genetics of reading disabilities: from phenotypes to candidate genes. [europepmc]
• Imaging-genetics in dyslexia: connecting risk genetic variants to brain neuroimaging and ultimately to reading impairments. [europepmc]
• Genome-wide association study of shared components of reading disability and language impairment. [europepmc]
• Neuropsychopathological comorbidities in learning disorders. [europepmc]
• Characterization of the DYX2 locus on chromosome 6p22 with reading disability, language impairment, and IQ. [europepmc]
• The DCDC2/intron 2 deletion and white matter disorganization: focus on developmental dyslexia. [europepmc]
• Mutation of Dcdc2 in mice leads to impairments in auditory processing and memory ability. [europepmc]
• The DYX2 locus and neurochemical signaling genes contribute to speech sound disorder and related neurocognitive domains. [europepmc]
• Strong motion deficits in dyslexia associated with DCDC2 gene alteration. [europepmc]
• The regulatory element READ1 epistatically influences reading and language, with both deleterious and protective alleles. [europepmc]
• Mutations in DCDC2 (doublecortin domain containing protein 2) in neonatal sclerosing cholangitis. [europepmc]
• Study of Genetic Association With DCDC2 and Developmental Dyslexia in Hong Kong Chinese Children. [europepmc]
• A molecular-genetic and imaging-genetic approach to specific comprehension difficulties in children. [europepmc]
• Effect of READ1 on latent profiles of reading disorder and comorbid attention and language impairment subtypes. [europepmc]
• DCDC2 READ1 regulatory element: how temporal processing differences may shape language. [europepmc]
• Identifying Dyslexia: Link between Maze Learning and Dyslexia Susceptibility Gene, DCDC2, in Young Children. [europepmc]
• Orthographic Depth May Influence the Degree of Severity of Maze Learning Performance in Children at Risk for Reading Disorder. [europepmc]
• Phonological awareness mediates the relationship between DCDC2 and reading performance with home environment. [europepmc]
• Targeted analysis of dyslexia-associated regions on chromosomes 6, 12 and 15 in large multigenerational cohorts. [europepmc]