Genetic Animal Models for Absence Epilepsy: A Review of the WAG/Rij Strain of Rats

2003/11/01 by A. M. L. Coenen, A.M.L. Coenen, E. L. J. M. van Luijtelaar +1 · 27 citations
Neuroscience · Medicine · #Neuroscience and Neuropharmacology Research #Epilepsy research and treatment #Photoreceptor and optogenetics research

paper · doi:10.1023/a:1026179013847

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• Elevated thalamic low-voltage-activated currents precede the onset of absence epilepsy in the SNAP25-deficient mouse mutant coloboma. [europepmc]
• Consciousness and epilepsy: why are patients with absence seizures absent? [europepmc]
• Impaired regulation of thalamic pacemaker channels through an imbalance of subunit expression in absence epilepsy. [europepmc]
• Deep layer somatosensory cortical neurons initiate spike-and-wave discharges in a genetic model of absence seizures. [europepmc]
• Early treatment suppresses the development of spike-wave epilepsy in a rat model. [europepmc]
• DTI abnormalities in anterior corpus callosum of rats with spike-wave epilepsy. [europepmc]
• Genetics of complex neurological disease: challenges and opportunities for modeling epilepsy in mice and rats. [europepmc]
• Differential regulation of HCN channel isoform expression in thalamic neurons of epileptic and non-epileptic rat strains. [europepmc]
• Where fMRI and electrophysiology agree to disagree: corticothalamic and striatal activity patterns in the WAG/Rij rat. [europepmc]
• Epilepsy as a neurodevelopmental disorder. [europepmc]
• Searching for the ideal antiepileptogenic agent in experimental models: single treatment versus combinatorial treatment strategies. [europepmc]
• Spike-wave discharges in adult Sprague-Dawley rats and their implications for animal models of temporal lobe epilepsy. [europepmc]
• How can we identify ictal and interictal abnormal activity? [europepmc]
• Matrix metalloproteinase-9 involvement in the structural plasticity of dendritic spines. [europepmc]
• Dynamics of networks during absence seizure's on- and offset in rodents and man. [europepmc]
• Critical Roles of the Direct GABAergic Pallido-cortical Pathway in Controlling Absence Seizures. [europepmc]
• Tapping the Brakes: Cellular and Synaptic Mechanisms that Regulate Thalamic Oscillations. [europepmc]
• Exogenous Ketone Supplements Reduce Anxiety-Related Behavior in Sprague-Dawley and Wistar Albino Glaxo/Rijswijk Rats. [europepmc]
• Adenosine A1 Receptor Antagonism Abolished the Anti-seizure Effects of Exogenous Ketone Supplementation in Wistar Albino Glaxo Rijswijk Rats. [europepmc]
• Methodological standards and interpretation of video-electroencephalography in adult control rodents. A TASK1-WG1 report of the AES/ILAE Translational Task Force of the ILAE. [europepmc]
• Altered Cortical and Hippocampal Excitability in TgF344-AD Rats Modeling Alzheimer's Disease Pathology. [europepmc]
• Validated animal models for antiseizure drug (ASD) discovery: Advantages and potential pitfalls in ASD screening. [europepmc]
• Is There a Future for PPARs in the Treatment of Neuropsychiatric Disorders? [europepmc]
• Targeting Ionotropic Glutamate Receptors in the Treatment of Epilepsy. [europepmc]