Morphogenetic constraints in the development of gastruloids: Implications for mouse gastrulation

2025/08/21 by Ulla-Maj Fiuza, Ulla-Maj Fiúza, Sara Bonavia +9 · 1 voice · 9 citations
Biochemistry, Genetics and Molecular Biology · #Digestive system and related health

paper · doi:10.1016/j.cdev.2025.204043

Cited by

• Tissue phase transitions in development: more than just mechanics
• Tissue surface mechanics constrains proliferation-driven forces to guide mammalian body axis elongation
• N2B27 media formulations influence gastruloid development
• Dynamical systems of fate and form in development. [europepmc]
• Fine-tuning mechanical constraints reveals uncoupled patterning and gene expression programs in murine gastruloids. [europepmc]
• N2B27 media formulations influence gastruloid development. [europepmc]
• Mosaic gastruloids reveal a temporal restriction for developmental cell competition. [europepmc]
• The proteomic landscape and temporal dynamics of human and mouse gastruloid development. [europepmc]
• Retinoic Acid Receptor γ Activity Plays a Critical Role in Regulating Early Mouse Gastruloid Development. [europepmc]

Discussions

• In this intriguing paper published from the lab of @amartinezarias.bsky.social , they looked at the effects of size on morphology, tissue composition, and gene expression of gastruloid development. Th [bsky, 17 points, 0 comments]