2017/06/01 by Saeed Samarghandian, Tahereh Farkhondeh, Mohsen Azimi–Nezhad · 1 citation
Medicine · Agricultural and Biological Sciences · Chemistry · #Flavonoids in Medical Research #Bee Products Chemical Analysis #Silymarin and Mushroom Poisoning #Chrysin #Pharmacology #Chemistry #Medicine #Traditional medicine #Antioxidant #Biochemistry
paper · pdf · doi:10.1177/1559325817711782
openalex publication_date 2017/06/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/30
ISSUES: Polyphenolic compounds, especially flavonoids, are known as the most common chemical class of phytochemicals, which possess a multiple range of health-promoting effects. Flavonoids are ubiquitous in nature. They are also present in food, providing an essential link between diet and prevention of several diseases. APPROACH: Chrysin (CH), a natural flavonoid, was commonly found in propolis and honey and traditionally used in herbal medicine. A growing body of scientific evidence has shown that CH possesses protective effects against toxic agents in various animal tissues, including brain, heart, liver, kidney, and lung. KEY FINDINGS: This study found that CH may be effective in disease management induced by toxic agents. However, due to the lack of information on human, further studies are needed to determine the efficacy of CH as an antidote agent in human. CONCLUSION: The present article aimed to critically review the available literature data regarding the protective effects of CH against toxic agent-induced toxicities as well as its possible mechanisms.