Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

2013/01/08 by Chia-Chen Liu, Chia‐Chen Liu, Takahisa Kanekiyo +2 · 7 citations
Computer Science · Medicine · Neuroscience · #Allele #Alzheimer's disease #Alzheimer's disease research and treatments #Apolipoprotein E #Biology #Cerebral amyloid angiopathy #Cholinesterase and Neurodegenerative Diseases #Cognitive decline #Computational Drug Discovery Methods #Dementia #Disease #Endocrinology #Gene #Genetics #Internal medicine #Medicine #Neurodegeneration #Neuroinflammation #Neuroscience #Receptor #TREM2

paper · doi:10.1038/nrneurol.2012.263

crossref issued 2013/01/08 · crossref published 2013/01/08 · crossref published-online 2013/01/08 · openalex publication_date 2013/01/08 · crossref created 2013/01/08 · crossref published-print 2013/02/01 · openalex created_date 2016/06/24 · crossref deposited 2024/05/04 · openalex updated_date 2026/08/05 · crossref indexed 2026/08/06

Citations

• Head injury as a risk factor for Alzheimer's disease: the evidence 10 years on; a partial replication
• Overexpression of Low-Density Lipoprotein Receptor in the Brain Markedly Inhibits Amyloid Deposition and Increases Extracellular Aβ Clearance
• A PPARγ-LXR-ABCA1 Pathway in Macrophages Is Involved in Cholesterol Efflux and Atherogenesis
• Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families
• A large study reveals no association between APOE and Parkinson's disease
• Predictive value of APOE- 4 allele for progression from MCI to AD-type dementia: a meta-analysis
• Mild Cognitive Impairment
• Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound‐B
• Fibrillar amyloid-β burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease

Cited by

• Regulation of beta-amyloid production in neurons by astrocyte-derived cholesterol
• Shorter Telomere Length in Carriers of APOE-ε4 and High Plasma Concentration of Glucose, Glyoxal and Other Advanced Glycation End Products (AGEs)
• Regulation of beta-amyloid production in neurons by astrocyte-derived cholesterol
• Alzheimer’s Disease: Biomarkers in the Genome, Blood, and Cerebrospinal Fluid
• Alzheimer’s disease basics: we all should know
• Multi-Modal Detection of Alzheimer's Disease from Speech and Text
• Apolipoprotein E [wikipedia]