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Impact of deviation from precise balance of spike-timing-dependent plasticity

2002/11/22 by Narihisa Matsumoto, Masato Okada, Matsumoto, Narihisa +1
Biochemistry, Genetics and Molecular Biology · Engineering · Neuroscience · Physics and Astronomy · #Advanced Memory and Neural Computing #Disordered Systems and Neural Networks (cond-mat.dis-nn) #FOS: Biological sciences #FOS: Physical sciences #Neural dynamics and brain function #Neuroscience and Neural Engineering #Quantitative Biology (q-bio) #cond-mat.dis-nn #q-bio

paper · pdf · doi:10.48550/arxiv.cond-mat/0211503

24 pages, 5 figures

openalex publication_date 2002/11/22 · arxiv created 2004/03/15 · arxiv updated 2009/11/30 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

Recent biological experimental findings have shown that synaptic plasticity depends on the relative timing of pre- and post-synaptic spikes and this is called spike-timing-dependent plasticity (STDP). Many authors have claimed that a precise balance between long-term potentiation (LTP) and long-term depression (LTD) of STDP is crucial in the storage of spatio-temporal patterns. Some authors have numerically investigated the impact of an imbalance between LTP and LTD on the network properties. However, the mathematical mechanism remains unknown. We analytically show that an associative memory network has the robust retrieval properties of spatio-temporal patterns, and these properties make the network less vulnerable to any deviation from a precise balance between LTP and LTD when the network contains a finite number of neurons.

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