1991/08/30 by Simon LeVay · 3 citations
Medicine · Psychology · Neuroscience · #Hypothalamic control of reproductive hormones #Evolutionary Psychology and Human Behavior #Regulation of Appetite and Obesity #Sexual dimorphism #Sexual orientation #Hypothalamus #Sexual behavior #Psychology #Heterosexuality #Internal medicine #Homosexuality #Endocrinology #Biology #Developmental psychology #Medicine #Social psychology
paper · doi:10.1126/science.1887219
openalex publication_date 1991/08/30 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/30
The anterior hypothalamus of the brain participates in the regulation of male-typical sexual behavior. The volumes of four cell groups in this region [interstitial nuclei of the anterior hypothalamus (INAH) 1, 2, 3, and 4] were measured in postmortem tissue from three subject groups: women, men who were presumed to be heterosexual, and homosexual men. No differences were found between the groups in the volumes of INAH 1, 2, or 4. As has been reported previously, INAH 3 was more than twice as large in the heterosexual men as in the women. It was also, however, more than twice as large in the heterosexual men as in the homosexual men. This finding indicates that INAH is dimorphic with sexual orientation, at least in men, and suggests that sexual orientation has a biological substrate.