2017/03/17 by Malbor Asllani, Timoteo Carletti · 1 citation
Physics and Astronomy · #nlin.AO
paper · pdf · doi:10.1371/journal.pcbi.1006296
published as PLoS Comput Biol 14(7): e1006296 (2018)
arxiv created 2017/03/17 · arxiv updated 2018/10/02
Many coordination phenomena in Nature are grounded on a synchronisation regime. In the case of brain dynamics, such self-organised process allows the neurons of particular brain regions to behave as a whole and thus directly controlling the neural activity, the muscles and finally the whole human body. However, not always such synchronised collective behaviour is the desired one, this is the case of neurodegenerative diseases such as Parkinson's or epilepsy where abnormal synchronisation induces undesired effects such as tremors and epileptic seizures. In this paper we propose an innovative, minimally invasive, control method able to effectively desynchronise the interested brain zones and thus to reduce the onset of undesired behaviour.