2007/12/01 by Rebecca Vaughan, Simone Vitali, Paul Eden +8 · 1 citation
Medicine · Immunology and Microbiology · #Fungal Infections and Studies #Antifungal resistance and susceptibility #Toxoplasma gondii Research Studies #Cryptococcosis #Cryptococcus neoformans #Biology #Cryptococcus #Cryptococcus gattii #Pathology #Immunology #Medicine #Microbiology
paper · doi:10.1638/2007-0005r.1
openalex publication_date 2007/12/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/19
Two cases of fatal cryptococcosis are described, one of Cryptococcus neoformans infection in a Gilbert's potoroo (Potorous gilbertii) and one of Cryptococcus gattii infection in a long-nosed potoroo (Potorous tridactylus). The diagnoses were confirmed by culture and specific immunohistochemistry, respectively. The long-nosed potoroo tested positive using the latex cryptococcal antigen test (LCAT), whereas the Gilbert's potoroo had a negative LCAT result despite having advanced disease of some duration. In both cases, the clinical presentation was a progressive neurologic disease associated with a central nervous system infection. Pulmonary infection was also observed in the long-nosed potoroo. Specific treatment with antifungal agents was unsuccessful in the long-nosed potoroo.