2016/01/06 by Sanli Faez, Faez, Sanli
Physics and Astronomy · #Experimental and Theoretical Physics Studies #FOS: Physical sciences #Optics (physics.optics) #Soft Condensed Matter (cond-mat.soft)
paper · pdf · doi:10.48550/arxiv.1601.01226
openalex publication_date 2016/01/06 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
A highly sensitive optical capillary electrophoresis measurement method based on a nanofluidic optical fiber platform is presented. By using scaling arguments and considering realistic instrument limitations, I underline the feasibility of measuring the electrophoretic mobility of a single freely-diffusing nanoparticle or macromolecule in vitro, continuously and indefinitely, with microsecond time resolution. The high speed of this technique opens up new possibilities for studying reaction kinetics at the single molecule level.