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Kleine–Levin Syndrome: History and Brief Review

2008/01/01 by J. Pearce · 1 citation
Neuroscience · Psychology · Medicine · #Sleep and Wakefulness Research #Memory and Neural Mechanisms #Circadian rhythm and melatonin #Psychology #Medicine #Psychiatry #Psychoanalysis

paper · doi:10.1159/000148694

openalex publication_date 2008/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/15

Abstract

Episodic hypersomnia, compulsive excessive eating and erotic behaviour, with schizophrenic-like mental symptoms are the hallmarks of the rare Kleine-Levin syndrome. This paper traces the origins of its description back to the 18th century and the changing concepts of its complex organic-psychogenic aetiology. The eventual, spontaneous disappearance of the syndrome is unexplained.

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