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A validated patient-specific FSI model for vascular access in haemodialysis

2017/04/25 by W. P. Guess, A. M. de Villiers, Andrew McBride +8
Biochemistry, Genetics and Molecular Biology · Engineering · Health Professions · Medicine · Physics and Astronomy · #Biomedical engineering #Blood flow #Central Venous Catheters and Hemodialysis #Composite material #Coronary Interventions and Diagnostics #Engineering #Finite element method #Flow (mathematics) #Fluid–structure interaction #Hemodialysis #Magnetic resonance imaging #Materials science #Mechanics #Medicine #Physics #Radiology #Shear stress #Structural engineering #Surgery #Vascular Procedures and Complications #Vascular access #physics.med-ph #q-bio.QM

paper · pdf · doi:10.1007/s10237-017-0973-8

21 pages, 6 png figures, 11 pdf figures, uses myarX.cls

arxiv created 2017/04/25 · openalex publication_date 2017/11/14 · arxiv updated 2018/01/30 · openalex created_date 2020/11/23 · openalex updated_date 2026/08/05

Abstract

A patient-specific fluid-structure interaction (FSI) model of a phase-contrast magnetic resonance angiography (PC-MRA) imaged arteriovenous fistula is presented. The numerical model is developed and simulated using a commercial multiphysics simulation package where a semi-implicit FSI coupling scheme combines a finite volume method blood flow model and a finite element method vessel wall model. A pulsatile mass-flow boundary condition is prescribed at the artery inlet of the model, and a three-element Windkessel model at the artery and vein outlets. The FSI model is freely available for analysis and extension. This work shows the effectiveness of combining a number of stabilisation techniques to simultaneously overcome the added-mass effect and optimise the efficiency of the overall model. The PC-MRA data, fluid model, and FSI model results show almost identical flow features in the fistula; this applies in particular to a flow recirculation region in the vein that could potentially lead to fistula failure.

Citations