2005/01/01 by Maciej Henneberg, Christoph Stephan, R. Norris +4 · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · Psychology · #Biology #Biotin and Related Studies #Citation #Computer science #Geography #Library science #Primate Behavior and Ecology #Science, Research, and Medicine #Variation (astronomy) #World Wide Web
paper · pdf · doi:10.1002/ajpa.20217
openalex publication_date 2005/01/01 · openalex created_date 2022/10/05 · openalex updated_date 2026/07/23
Functional interpretation of limb bone cross-sectional geometry depends upon knowledge of the magnitude and direction of habitual loading. Quantification of bone loading has only been possible using invasive, in vivo strain measurement and a non-invasive alternative is highly desirable. This study presents a new biomechanical model that predicts bone loading conditions from non-invasive 3D kinematic and ground reaction force data. The model has been validated using simultaneous strain, ground reaction force and kinematic data obtained in vitro from an aluminum limb model, and in vivo from experiments on sheep metatarsals. Preliminary results suggest that the orientation of the neutral axis of bending, and its position on the bone cross section, can be determined from the non-invasive force and kinematic data. These data can be used to predict the orientation and magnitude of bone bending in distal limb segments suggesting that this model will inform studies relating bone cross-sectional geometry to loading conditions and locomotor behaviors.