A Gene Wiki for Community Annotation of Gene Function

2008/07/03 by Jon W. Huss, Camilo Madariaga Orozco, James Goodale +5 · 6 citations
Biochemistry, Genetics and Molecular Biology · #Genetics, Bioinformatics, and Biomedical Research #Gene expression and cancer classification #Bioinformatics and Genomic Networks #Biology #Annotation #Function (biology) #Gene #Computational biology #Gene Annotation #Genetics #Genome

paper · pdf · doi:10.1371/journal.pbio.0060175

openalex publication_date 2008/07/03 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/05

Abstract

Gene portals (e.g., Entrez Gene [1] and Ensembl [2]) and model organism databases (e.g., Mouse Genome Database [3], Rat Genome Database [4], FlyBase [5]) are popular and useful tools for researching gene annotation and enforcing data standards.These databases provide a large volume and diversity of information on each gene, including protein and transcript sequences, genome location, genomic structure, aliases, links to literature, and gene function.These sites are considered to be the definitive sources for these types of gene annotation.However, by their very nature as

Citations

• Internet encyclopaedias go head to head
• Emergence of scaling in random networks
• A gene atlas of the mouse and human protein-encoding transcriptomes

Cited by

• The Gene Wiki: community intelligence applied to human gene annotation
• Mining the Gene Wiki for functional genomic knowledge
• Gene Wiki Reviews: Marrying crowdsourcing with traditional peer review
• The Gene Wiki in 2011: community intelligence applied to human gene annotation
• Linking genes to diseases with a SNPedia-Gene Wiki mashup
• Gene Wiki [wikipedia]

Related

• The Gene Wiki: community intelligence applied to human gene annotation
• The Gene Wiki in 2011: community intelligence applied to human gene annotation
• The Gene Ontology resource: enriching a GOld mine
• Mining the Gene Wiki for functional genomic knowledge
• The Gene Ontology knowledgebase in 2026