2017/05/31 by E. Werner, Erik Werner, Guo Kang Cheong +5
Biochemistry, Genetics and Molecular Biology · Chemistry · Engineering · Mathematics · Physics and Astronomy · #Classical mechanics #Computer science #Electrostatics and Colloid Interactions #Extension (predicate logic) #Geometry #Mathematics #Microfluidic and Capillary Electrophoresis Applications #Nanopore and Nanochannel Transport Studies #Odds #Parameter space #Physics #Scaling #Scaling law #Space (punctuation) #Statistical physics #Theoretical physics #physics.bio-ph #q-bio.BM
paper · pdf · doi:10.1103/physrevlett.119.268102
published as Phys. Rev. Lett. 119, 268102 (2017) · Revised version. 5 pages, 4 figures, revised version, supplementary information
arxiv created 2017/12/13 · openalex publication_date 2017/12/28 · arxiv updated 2018/01/03 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/06
Experiments measuring DNA extension in nanochannels are at odds with even the most basic predictions of current scaling arguments for the conformations of confined semiflexible polymers such as DNA. We show that a theory based on a weakly self-avoiding, one-dimensional "telegraph" process collapses experimental data and simulation results onto a single master curve throughout the experimentally relevant region of parameter space and explains the mechanisms at play.