2008/08/14 by Jaime Alonso Reséndiz‐Colosia, Sergio Rodríguez‐Cuevas, Rutilio Flores‐Díaz +4 · 1 citation
Medicine · #Parathyroid Disorders and Treatments #Hypertrophic osteoarthropathy and related conditions #Medical Imaging and Pathology Studies #Medicine #Brown tumor #Parathyroidectomy #Primary hyperparathyroidism #Osteitis fibrosa cystica #Lesion #Osteitis #Hyperparathyroidism #Maxilla #Surgery #Mandible (arthropod mouthpart) #Anatomy #Secondary hyperparathyroidism #Calcium #Internal medicine #Parathyroid hormone #Biology #Osteomyelitis
paper · doi:10.1002/hed.20905
openalex publication_date 2008/08/14 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/26
BACKGROUND: Brown tumor occasionally affects the facial bones. Clinically, these lesions can be mistaken for a neoplasm. Opinions are divided on the course of management of the bony lesions once parathyroidectomy has been carried out. METHODS: We treated 22 patients with primary hyperparathyroidism and osteitis fibrosa cystica and observed their clinical and biochemical recovery. RESULTS: Fifteen patients (68.2%) had brown tumors in mandible, and 7 (31.8%) in maxilla. After parathyroidectomy, 21 patients had normal total serum calcium values. All brown tumors presented a spontaneous progressive regression; in 18 cases, regression was total, with a mean time period of 10 months. Two patients had partial regression after nearly 2 years. Another 2 patients were lost to follow-up. CONCLUSIONS: After successful parathyroid surgery, the bony lesions tended to regress spontaneously, either partially or completely. However, if the lesion is disfiguring or symptomatic, surgical excision may be indicated.