2017/01/05 by Pauli Kehayias, P. Kehayias, A. Jarmola +20 · 1 citation
Chemistry · Earth and Planetary Sciences · Materials Science · Physics and Astronomy · #Analytical Chemistry (journal) #Chemistry #Condensed matter physics #Diamond #Diamond and Carbon-based Materials Research #Fluorine-19 NMR #Force Microscopy Techniques and Applications #High-pressure geophysics and materials #Materials science #Nanodiamond #Nuclear magnetic resonance #Nuclear magnetic resonance spectroscopy #Organic chemistry #Physics #Spectroscopy #Spins #Vacancy defect #cond-mat.mes-hall #physics.chem-ph #physics.ins-det #quant-ph
paper · pdf · doi:10.1038/s41467-017-00266-4
7 pages, 6 figures (main text) + 11 pages, 7 figures, 5 tables (Supplemental)
arxiv created 2017/01/05 · openalex created_date 2017/05/19 · openalex publication_date 2017/08/04 · arxiv updated 2017/11/01 · openalex updated_date 2026/08/05
Abstract Sensors using nitrogen-vacancy centers in diamond are a promising tool for small-volume nuclear magnetic resonance (NMR) spectroscopy, but the limited sensitivity remains a challenge. Here we show nearly two orders of magnitude improvement in concentration sensitivity over previous nitrogen-vacancy and picoliter NMR studies. We demonstrate NMR spectroscopy of picoliter-volume solutions using a nanostructured diamond chip with dense, high-aspect-ratio nanogratings, enhancing the surface area by 15 times. The nanograting sidewalls are doped with nitrogen-vacancies located a few nanometers from the diamond surface to detect the NMR spectrum of roughly 1 pl of fluid lying within adjacent nanograting grooves. We perform 1 H and 19 F nuclear magnetic resonance spectroscopy at room temperature in magnetic fields below 50 mT. Using a solution of CsF in glycerol, we determine that 4 ± 2 × 10 12 19 F spins in a 1 pl volume can be detected with a signal-to-noise ratio of 3 in 1 s of integration.