2012/03/12 · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · Mathematics · #Catalysis #Catalytic Alkyne Reactions #Chemistry #Computer science #Mathematics #Organic chemistry #Pauson–Khand reaction #Synthesis and Biological Activity #Synthetic Organic Chemistry Methods
paper · doi:10.1002/9781119941934
openalex publication_date 2012/03/12 · openalex created_date 2016/06/24 · openalex updated_date 2025/11/06
The Pauson-Khand reaction is an important reaction in the field of organic chemistry. It involves the transition-metal catalysed cycloaddition of an alkyne, an alkene and carbon monoxide, to produce cyclopentenones. The importance of this reaction originates from its high value in transforming simple components into the synthetically useful cyclopentenone unit, in which a high degree of molecular complexity can be achieved in a single step, with impressive stereochemical and regiochemical control. The Pauson-Khand Reaction investigates the nature and many variations of this reaction.