2010/01/01 by Bahaderjeet Singh, Ashok K. Chopra, Mohan Paul S. Ishar +2 · 33 citations
Biochemistry, Genetics and Molecular Biology · Medicine · Agricultural and Biological Sciences · Chemistry · #Advances in Cucurbitaceae Research #Phytochemical and Pharmacological Studies #Seed and Plant Biochemistry #Chemistry #Petroleum ether #Chloroform #Ethanol #Antifungal #Food science #Aspergillus niger #Candida albicans #Endosperm #Botany #Traditional medicine #Biochemistry #Extraction (chemistry) #Chromatography #Biology #Microbiology
paper · open access · doi:10.4103/0250-474x.65021
published in Indian Journal of Pharmaceutical Sciences 72(2), 261 (Medknow)
openalex publication_date 2010/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/06/11
Rudrakasha is the dried bead obtained from the ripe fruit of Elaeocarpus ganitrus Roxb. (Family: Elaeocarpaceae). Microscopic studies revealed the presence of a hard endocarp with lignified isodiametric sclereids, seeds with membranous seed coat, which enclosed a dense cellular endosperm comprising of calcium oxalate druses. Physicochemical parameters showed that total ash was 1.36 times and 1.56 times more than the acid insoluble ash and water-soluble ash, respectively. Further, ethanol had a maximum extractable value of 2.4% and moisture content was found to be 9.7%. Different extracts, petroleum ether, chloroform, ethanol and water were prepared. Chemically the extracts showed the presence of phytosterols, fats, alkaloids, flavonoids, carbohydrates, proteins and tannins. The extracts were evaluated for antifungal activity on different fungal strains. Chlorofom and ethanol extracts have high antifungal activity against Candida albicans. Whereas, chloroform, ethanol and water extracts showed moderate inhibition against Aspergillus niger.