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Phytochemical Study ofActaea rubraand Biological Screenings of Isolates

2006/10/01 by Zulfıqar Ali, Shabana Khan, Ikhlas Khan · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · Agricultural and Biological Sciences · Chemistry · #Natural product bioactivities and synthesis #Antioxidant Activity and Oxidative Stress #Phytochemistry and Biological Activities #Phytochemical #Terpene #Traditional medicine #Glucoside #Glycoside #Antioxidant #Saponin #Chemistry #Chemical constituents #Biology #Stereochemistry #Medicine #Biochemistry #Chromatography

paper · doi:10.1055/s-2006-951696

openalex publication_date 2006/10/01 · openalex created_date 2016/06/24 · openalex updated_date 2026/08/04

Abstract

A phytochemical study on the chemical constituents of the roots of Actaea rubra led to the isolation and characterization of eleven xylosides of 9,19-cyclolanostane type triterpenes including the new rubraside A (1) and a beta-sitosterol glucoside. The structures of the isolates were determined with the help of spectroscopic data including 2-dimensional NMR as well as comparison with reported data. The compounds were tested for cytotoxic, estrogenic, antioxidant, and anticomplement activities. They were found inactive in the tested assays, except for 4, which showed moderate anticomplement activity.

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