Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis

2011/03/13 by George F Mells, George Mells, James Floyd +34 · 6 citations
Medicine · #Allele #Biology #Celiac Disease Research and Management #Disease #Gene #Genetic association #Genetics #Genome-wide association study #Genotype #Haplotype #Immunology #Imputation (statistics) #Internal medicine #Linkage disequilibrium #Liver Disease Diagnosis and Treatment #Liver Diseases and Immunity #Locus (genetics) #Medicine #Missing data #Population #Primary biliary cirrhosis #Primary sclerosing cholangitis #Single-nucleotide polymorphism

paper · doi:10.1038/ng.789

crossref issued 2011/03/13 · crossref published 2011/03/13 · crossref published-online 2011/03/13 · openalex publication_date 2011/03/13 · crossref created 2011/03/13 · crossref published-print 2011/04/01 · crossref deposited 2023/06/05 · openalex created_date 2025/10/10 · crossref indexed 2026/08/01 · openalex updated_date 2026/08/04

Citations

• A Unified Approach to Genotype Imputation and Haplotype-Phase Inference for Large Data Sets of Trios and Unrelated Individuals
• PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses

Cited by

• Immunochip analyses identify a novel risk locus for primary biliary cirrhosis at 13q14, multiple independent associations at four established risk loci and epistasis between 1p31 and 7q32 risk variants
• POGLUT1, the putative effector gene driven by rs2293370 in primary biliary cholangitis susceptibility locus chromosome 3q13.33
• The Immunobiology and Pathophysiology of Primary Biliary Cirrhosis
• Primary biliary cholangitis
• Sex and Age Are Determinants of the Clinical Phenotype of Primary Biliary Cirrhosis and Response to Ursodeoxycholic Acid
• Primary biliary cholangitis [wikipedia]