2013/07/22 by Ruoling Chen, Zhi Hu, Sophie Orton +2 · 1 citation
Environmental Science · Medicine · Psychology · #Association (psychology) #Causality (physics) #Cognition #Cognitive decline #Cognitive disorder #Cognitive impairment #Cohort #Cohort study #Confidence interval #Dementia #Disease #Environmental health #Geriatrics #Gerontology #Health, Environment, Cognitive Aging #Internal medicine #Medicine #Nutritional Studies and Diet #Passive smoking #Psychiatry #Psychology #Relative risk #Risk factor #Smoking Behavior and Cessation
paper · doi:10.1177/0891988713496165
openalex publication_date 2013/07/22 · openalex created_date 2016/06/24 · openalex updated_date 2026/08/04
Association of passive smoking with cognitive impairment in older adults is unclear. We carried out a systematic literature review and a new study to determine the association. There were 3 cross-sectional studies published, showing a significant association of passive smoking with cognitive impairment (a relative risk (RR) of about 1.30-1.90). In the new cohort study, we interviewed 1081 never-smoking participants aged ≥ 65 years in China using a standard method of the Geriatric Mental State-Automated Geriatric Examination for Computer Assisted Taxonomy and found a significant association with dose response; multivariate adjusted RR was 1.02 (95% confidence interval 0.67-1.55) in > 0 to 49 exposure level years of passive smoking, 1.57 (1.00-2.47) in 50 to 99, and 2.12 (1.24-3.63) in ≥ 100, trend P = .008. The relationship seems not to be a reverse causality of the effect. Passive smoking could be considered an important risk factor for cognitive impairment in older adults. Avoiding exposure to passive smoking would help to preserve cognitive decline in later life.