2017/08/05 by Ru‐Xin Foong, Helen A. Brough · 1 citation
Medicine · #Food Allergy and Anaphylaxis Research #Contact Dermatitis and Allergies #Allergic Rhinitis and Sensitization #Peanut allergy #Sensitization #Allergy #Medicine #Egg allergy #Asthma #Filaggrin #Food allergy #Anaphylaxis #Immunology #Allergen #Skin barrier #Dermatology #Atopic dermatitis
paper · doi:10.1111/cea.12992
openalex publication_date 2017/08/05 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/26
The prevalence of peanut allergy has increased over the years and still remains one of the most common causes of food-related anaphylaxis. The way in which peanut sensitization occurs has been explored, such as via maternal consumption in pregnancy, via breastmilk and through a disrupted skin barrier. It has previously been shown that environmental exposure to aeroallergens in household dust can be a risk factor for the development of allergic asthma. There is an increasing body of evidence that the combination of cutaneous sensitization via a disrupted skin barrier (ie children with eczema or with filaggrin mutations) and environmental peanut exposure influences the development of peanut allergy. This review aims to explore routes of peanut sensitization and the current evidence on how environmental exposure to peanut affects the development of peanut allergy.