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Factor V Leiden: How great is the risk of venous thromboembolism?

2012/04/01 by Khaldoon Shaheen, M. Chadi Alraies, Abdul Hamid Alraiyes +1 · 1 citation
Medicine · #Blood Coagulation and Thrombosis Mechanisms #Venous Thromboembolism Diagnosis and Management #Atrial Fibrillation Management and Outcomes #Medicine #Factor V Leiden #Thrombophilia #Venous thromboembolism #Venous thrombosis #Concomitant #Risk factor #Thrombosis #Pulmonary embolism #Internal medicine #Surgery

paper · pdf · doi:10.3949/ccjm.79a.11072

openalex publication_date 2012/04/01 · openalex created_date 2016/06/24 · openalex updated_date 2026/07/31

Abstract

The factor V Leiden mutation, the most common inherited cause of thrombophilia, causes a mild hypercoagulable state. We describe a 29-year-old man, heterozygous for factor V Leiden, who developed extensive pulmonary emboli with concomitant bilateral deep venous thrombosis, likely provoked by prolonged immobility during a car trip. We then review the diagnosis, therapy, screening, and prognosis of venous thromboembolism related to factor V Leiden.

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