2018/01/24 by Vı́ctor Borrell · 1 citation
Neuroscience · Biochemistry, Genetics and Molecular Biology · #Neurogenesis and neuroplasticity mechanisms #Axon Guidance and Neuronal Signaling #Microtubule and mitosis dynamics #Neuroscience #Cerebral cortex #Biology #Cortex (anatomy)
paper · pdf · doi:10.1523/jneurosci.1106-17.2017
openalex publication_date 2018/01/24 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01
Folding of the cerebral cortex is as highly intriguing as poorly understood. At first sight, this may appear as simple tissue crumpling inside an excessively small cranium, but the process is clearly much more complex and developmentally predetermined. Whereas theoretical modeling supports a critical role for biomechanics, experimental evidence demonstrates the fundamental role of specific progenitor cell types, cellular processes, and genetic programs on cortical folding. Dual Perspectives Companion Paper: How Forces Fold the Cerebral Cortex, by Christopher D. Kroenke and Philip V. Bayly