2014/01/01 by Ki Tae Suk · 1 citation
Medicine · #Alcohol Consumption and Health Effects #Liver Disease Diagnosis and Treatment #Diet, Metabolism, and Disease #Alcoholic hepatitis #Alcoholic liver disease #Medicine #Abstinence #Hepatocellular carcinoma #Fatty liver #Cirrhosis #Liver disease #Pentoxifylline #Internal medicine #Disease #Gastroenterology #Psychiatry
paper · pdf · doi:10.3748/wjg.v20.i36.12934
openalex publication_date 2014/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/16
The excess consumption of alcohol is associated with alcoholic liver diseases (ALD). ALD is a major healthcare problem, personal and social burden, and significant reason for economic loss worldwide. The ALD spectrum includes alcoholic fatty liver, alcoholic hepatitis, cirrhosis, and the development of hepatocellular carcinoma. The diagnosis of ALD is based on a combination of clinical features, including a history of significant alcohol intake, evidence of liver disease, and laboratory findings. Abstinence is the most important treatment for ALD and the treatment plan varies according to the stage of the disease. Various treatments including abstinence, nutritional therapy, pharmacological therapy, psychotherapy, and surgery are currently available. For severe alcoholic hepatitis, corticosteroid or pentoxifylline are recommended based on the guidelines. In addition, new therapeutic targets are being under investigation.