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Induction of micronuclei in mice exposed to static magnetic fields

2001/11/01 by Yuji Suzuki · 2 citations
Biochemistry, Genetics and Molecular Biology · Medicine · Chemistry · #Electromagnetic Fields and Biological Effects #Magnetic and Electromagnetic Effects #Spaceflight effects on biology #Micronucleus test #Micronucleus #Clastogen #Bone marrow #Biology #Chemistry #Molecular biology #Immunology #Toxicity

paper · pdf · doi:10.1093/mutage/16.6.499

openalex publication_date 2001/11/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/30

Abstract

The aim of this experiment was to investigate whether static magnetic fields (SMFs) have cytogenetic effects in mouse bone marrow cells. The frequency of micronuclei was significantly increased by exposure of mice to 3.0 T for 48 and 72 h and 4.7 T for 24, 48 and 72 h. The increase in micronucleus frequency was dose dependent at all times. Micronucleus frequency at 4.7 T was higher than at 3.0 T. We consider that the increased numbers of micronuclei may be attributable to a stress reaction caused by SMFs or a direct clastogenic/spindle disturbance effect of SMFs.

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