Genomic instability in laminopathy-based premature aging

2005/06/26 by Baohua Liu, Jianming Wang, Kui Ming Chan +25 · 5 citations
Biochemistry, Genetics and Molecular Biology · #Biology #Cancer research #Cell biology #Chromosome #Chromosome instability #DNA #DNA Repair Mechanisms #DNA damage #DNA repair #Gene #Genetics #Genome instability #Lamin #Molecular biology #Nuclear Structure and Function #Nuclear lamina #Nuclear protein #Premature aging #RNA Research and Splicing #Transcription factor

paper · doi:10.1038/nm1266

crossref issued 2005/06/26 · crossref published 2005/06/26 · crossref published-online 2005/06/26 · openalex publication_date 2005/06/26 · crossref created 2005/06/26 · crossref published-print 2005/07/01 · crossref deposited 2022/03/25 · openalex created_date 2025/10/10 · crossref indexed 2026/07/24 · openalex updated_date 2026/07/25

Citations

• Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome
• Lamin A Truncation in Hutchinson-Gilford Progeria
• Pathway of incorporation of microinjected lamin A into the nuclear envelope.

Cited by

• Lamin A-Dependent Nuclear Defects in Human Aging
• Age-related changes of nuclear architecture in Caenorhabditis elegans
• Nuclear DNA Damage as a Direct Cause of Aging
• Rapamycin Reverses Cellular Phenotypes and Enhances Mutant Protein Clearance in Hutchinson-Gilford Progeria Syndrome Cells
• Progeria [wikipedia]