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On the binding of iabelled saxitoxin to the squid giant axon

1984/12/31 by R. D. Keynes, Joseph Murdoch Ritchie · 1 citation
Environmental Science · Neuroscience · Agricultural and Biological Sciences · Chemistry · Mathematics · #Marine Toxins and Detection Methods #Photoreceptor and optogenetics research #Cephalopods and Marine Biology #Squid giant axon #Loligo #Saxitoxin #Squid #Axon #Chemistry #Square (algebra) #Biophysics #Anatomy #Biology #Mathematics #Fishery #Biochemistry #Toxin #Geometry

paper · doi:10.1098/rspb.1984.0055

openalex publication_date 1984/12/31 · openalex created_date 2016/06/24 · openalex updated_date 2026/07/28

Abstract

Measurement of the maximum saturable binding capacity for 3H-labelled saxitoxin in well cleaned giant axons from Loligo forbesi gave a value of 290 +/- 65 (s.e.m.) binding sites per square micrometre of membrane. In samples of the fin nerve the total saturable uptake was 12.4 +/- 2.4 fmol mg-1 wet mass, corresponding to 94 sites per square micrometre for fibres whose mean diameter after fixation and embedding was estimated as 16 micron.

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