2015/01/01 by Süleyman Çetinkünar, Hasan Erdem, Recep Aktimur +1 · 1 citation
Medicine · #Pharmacology and Obesity Treatment #Bariatric Surgery and Outcomes #Diet and metabolism studies #Medicine #Obesity #Diabetes mellitus #Disease #Type 2 Diabetes Mellitus #Adipose tissue #Psychosocial #Type 2 diabetes #Pathophysiology #Weight loss #Intensive care medicine #Concomitant #Surgery #Bioinformatics #Internal medicine #Endocrinology #Psychiatry
paper · doi:10.12998/wjcc.v3.i6.504
openalex publication_date 2015/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/15
Obesity and diabetes is a co-pandemic and a major health concern that is expanding. It has many psychosocial and economic consequences due to morbidity and mortality of this disease combination. The pathophysiology of obesity and related diabetes is complex and multifactorial. One arm of this disease process is the genetic susceptibility. Other arm is dependent on the intricate neuro-humoral factors that converge in the central nerve system. Gut hormones and the adipose tissue derived factors plays an important role in this delicate network. Bariatric surgery provides the only durable option for treatment of obesity and furthermore it provides a remission in the concomitant diseases that accompany obesity. This review provides a brief insight to all these mechanisms and tries to deduce the possible reasons of remission of type 2 diabetes after bariatric surgery.