2006/02/03 by Doron M. Behar, Ene Metspalu, Toomas Kivisild +18 · 22 citations
Arts and Humanities · Biochemistry, Genetics and Molecular Biology · Medicine · Social Sciences · #Archaeology #Biology #Demography #Event (particle physics) #Forensic Anthropology and Bioarchaeology Studies #Forensic and Genetic Research #Founder effect #Gene #Genealogy #Genetic genealogy #Genetics #Genotype #Haplotype #History #Medicine #Mitochondrial DNA #Population #Portrait #Race, Genetics, and Society #Sociology #Sports and Physical Education Studies
paper · pdf · doi:10.1086/500307
openalex publication_date 2008/01/01 · openalex created_date 2016/06/24 · openalex updated_date 2026/04/28
Both the extent and location of the maternal ancestral deme from which the Ashkenazi Jewry arose remain obscure. Here, using complete sequences of the maternally inherited mitochondrial DNA (mtDNA), we show that close to one-half of Ashkenazi Jews, estimated at 8,000,000 people, can be traced back to only 4 women carrying distinct mtDNAs that are virtually absent in other populations, with the important exception of low frequencies among non-Ashkenazi Jews. We conclude that four founding mtDNAs, likely of Near Eastern ancestry, underwent major expansion(s) in Europe within the past millennium.