1990/01/01 by George R. Pettit, Gordon M. Cragg, Sheo B. Singh +2 · 2 citations
Chemistry · Medicine · #Chemical synthesis and alkaloids #Cancer Treatment and Pharmacology #Citation #Computer science #Icon #Library science #Information retrieval #World Wide Web
paper · doi:10.1021/np50067a026
openalex publication_date 1990/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01
The Chinese medicinal plant Zephyranthes candida was found to contain a cytostatic constituent. Separation of a n-BuOH extract directed by results of a bioassay employing the P-388 lymphocytic leukemia led to trans-dihydronarciclasine [2] as the principal cytostatic agent with ED50 3.2 X 10(-3) micrograms/ml.