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Activation of the Interventricular Septum

1955/01/01 by Allen M. Scher, Allan C. Young, Arthur L. Malmgren +1 · 95 citations
Medicine · #Cardiomyopathy and Myosin Studies #Cardiac electrophysiology and arrhythmias #Advanced MRI Techniques and Applications #Interventricular septum #Endocardium #Anatomy #Cardiology #Electrical conduction system of the heart #Internal medicine #Heart septum #Depolarization #QRS complex #Medicine #Electrocardiography #Ventricle

paper · pdf · doi:10.1161/01.res.3.1.56

published in Circulation Research 3(1), 56-64 (Lippincott Williams & Wilkins)

openalex publication_date 1955/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/06/11

Abstract

Multipolar recording techniques have been used to study excitation of the canine interventricular septum. Activity commences in the mid left septal endocardium and slightly later near the right anterior papillary muscle. From these sites depolarization spreads over the endocardial surfaces, probably via the Purkinje tissue, at 1 m./sec. and through the septal thickness at one-third this speed. Near the upper septum, bilaterally and on the posterior right there is a lack of the rapid endocardial conduction. Septal contribution to the QRS is considered.

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