1987/05/01 by Richard L. Eastburn, Thomas R. Fritsche, Charles A. Terhune · 1 citation
Environmental Science · Immunology and Microbiology · Agricultural and Biological Sciences · Medicine · #Parasite Biology and Host Interactions #Aquaculture disease management and microbiota #Fish Biology and Ecology Studies #Eosinophilia #Nausea #Vomiting #Diarrhea #Asymptomatic #Gastroenterology #Abdominal pain #Internal medicine #Medicine #Weight loss #Feces #Peripheral blood #Biology #Microbiology
paper · doi:10.4269/ajtmh.1987.36.586
openalex publication_date 1987/05/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/06/11
Between 1974 and 1985, 10 patients were studied who presented with either gastrointestinal complaints or unexplained peripheral blood eosinophilia, and had eggs typical for N. salmincola recovered from their stools. Clinical findings in 8 of the 10 included increased frequency of bowel movements or diarrhea (6), peripheral blood eosinophilia (6), abdominal discomfort (5), nausea and vomiting (3), weight loss (2), and fatigue (2). Two were asymptomatic. Eight recalled eating fish prior to the onset of symptoms. Anthelminthic treatment consisting of three 2-g doses of niclosamide (2 patients) or two 50 mg/kg doses of bithionol (1 patient) proved effective. In the remaining individuals symptoms resolved slowly over several months.