Recent progress on Tourette syndrome

2021/09/07 by Keisuke Ueda, Kevin J. Black · 1 citation
Psychology · Neuroscience · Medicine · #Obsessive-Compulsive Spectrum Disorders #Autism Spectrum Disorder Research #Eating Disorders and Behaviors #Tourette syndrome #Tics #Neuroscience #Neuroimaging #Neurotransmitter systems #Movement disorders #Psychology #Mechanism (biology) #Psychiatry #Medicine #Dopamine #Disease #Pathology

paper · pdf · doi:10.12703/r/10-70

openalex publication_date 2021/09/07 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/15

Abstract

Tic disorders and Tourette syndrome are the most common movement disorders in children and are characterized by movements or vocalizations. Clinically, Tourette syndrome is frequently associated with comorbid psychiatric symptoms. Although dysfunction of cortical-striatal-thalamic-cortical circuits with aberrant neurotransmitter function has been considered the proximate cause of tics, the mechanism underlying this association is unclear. Recently, many studies have been conducted to elucidate the epidemiology, clinical course, comorbid symptoms, and pathophysiology of tic disorders by using laboratory studies, neuroimaging, electrophysiological testing, environmental exposure, and genetic testing. In addition, many researchers have focused on treatment for tics, including behavioral therapy, pharmacological treatment, and surgical treatment. Here, we provide an overview of recent progress on Tourette syndrome.

Citations

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Cited by

• Tourette syndrome [wikipedia]

Related

• Tics and Tourette syndrome
• Tourette’s syndrome and its borderland
• Recent advances in Tourette syndrome
• Tics and Tourette: a clinical, pathophysiological and etiological review
• Tourette Syndrome and Other Tic Disorders in Childhood, Adolescence and Adulthood