Seignot's paper on the treatment of Tourette's syndrome with haloperidol*

1997/09/01 by Hugh Rickards, Nicola Hartley, Mary M. Robertson · 2 citations
Psychology · Medicine · Neuroscience · #Obsessive-Compulsive Spectrum Disorders #Haloperidol #Tourette syndrome #Psychiatry #Psychology #Tourette's syndrome #Medicine #Pediatrics #Neuroscience #Dopamine

paper · doi:10.1177/0957154x9700803109

openalex publication_date 1997/09/01 · openalex created_date 2016/06/24 · openalex updated_date 2026/06/11

Abstract

The paper of Seignot in 1961 is the first clinical description of the use of haloperidol to treat the symptoms of Gilles de la Tourette syndrome (GTS). It is widely quoted in literature about GTS. However, it is not widely known that the single case involved had been subject to a frontal lobectomy prior to treatment with haloperidol. We present a translation of that paper and a discussion of its significance.

Cited by

• Tourette syndrome, associated conditions and the complexities of treatment
• Tourette syndrome [wikipedia]