2001/04/23 by Randolf Brehler, Birgitta Kütting, Guy Lodge +1 · 1 citation
Chemistry · Medicine · Social Sciences · #Allergy #Argument (complex analysis) #Commons #Contact Dermatitis and Allergies #Economics #Environmental health #Epidemiology #Government (linguistics) #House of Commons #Immunology #Incidence (geometry) #Intensive care medicine #Internal medicine #Latex allergy #Law #Law and economics #Legislation #Mandate #Medicine #Natural history #Parliament #Pathology #Philosophy #Plant-Derived Bioactive Compounds #Political and Economic history of UK and US #Political science #Politics #Public administration #Sensitization #Seriousness
paper · doi:10.1001/archinte.161.8.1057
openalex publication_date 2012/07/27 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/23
In the past 10 years, IgE-mediated allergy to natural rubber latex has become a significant health problem in industrialized countries, especially among health care workers, patients with congenital malformations, and children with a history of multiple surgical interventions. Curative treatment inducing immunological tolerance in formerly sensitized patients is experimental and not yet generally available. Therefore, it is important to be aware of the seriousness of latex allergy and to understand the risk factors leading to this allergy. Preventive measures are needed to decrease the incidence of natural rubber latex sensitization. This article gives a brief review of the current state of knowledge concerning latex allergy, including a definition of latex, epidemiological data, identified allergens, the clinical spectrum, diagnostic procedures, cross-reactions, preventive measures, the legislative background, and economics.