2021/09/06 by Charlotte Rowe, Aurore Deledalle, Abdel Halim Boudoukha · 25 citations
Medicine · Psychology · #Bipolar disorder #Clinical psychology #Cognition #Comorbidity #Depression (economics) #Gambling Behavior and Treatments #MEDLINE #Medicine #Meta-analysis #Obsessive-Compulsive Spectrum Disorders #Personality Disorders and Psychopathology #PsycINFO #Psychiatry #Psychology #Psychosis #Schizophrenia (object-oriented programming) #Systematic review
paper · pdf · doi:10.1002/jclp.23240
published in Journal of Clinical Psychology 78(4), 469-484 (Wiley)
openalex publication_date 2021/09/06 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/26
OBJECTIVE: Although there is a growing number of studies on psychiatric comorbidities of obsessive-compulsive disorder (OCD), controversy remains about the strength of associations between some disorders. We present a series of systematic reviews and meta-analyses examining four psychiatric disorders frequently associated with OCD-depression, bipolar disorder, substance abuse disorder and psychosis. METHODS: Three electronic databases were searched up to May 2017; PsycINFO, Medline, and Web of Science. Meta-analyses using random effects models were conducted. RESULTS: The meta-analyses found strong associations between all comorbidities and OCD, particularly for depression. In addition, a series of systematic reviews were conducted giving information about the characteristics of these psychiatric associations. CONCLUSION: It is probable that these disorders share common etiological factors, and thus trans-diagnostic processes must be addressed when offering treatment. Clinical implications of these findings are discussed with suggestions for further research in the area.