2017/11/09 by Meksianis Z. Ndii, Ndii, Meksianis Z.
Agricultural and Biological Sciences · Medicine · #Dynamical Systems (math.DS) #FOS: Biological sciences #FOS: Mathematics #Insect symbiosis and bacterial influences #Mosquito-borne diseases and control #Populations and Evolution (q-bio.PE)
paper · pdf · doi:10.48550/arxiv.1711.03607
openalex publication_date 2017/11/09 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
The introduction of Wolbachia-carrying mosquitoes into the population has\nrecently been proposed as an alternative strategy against dengue. Although\nlaboratory experiments have shown that the Wolbachia bacterium can reduce the\nlevels of dengue virus in mosquitoes, it is also important to assess the\nperformance of Wolbachia in reducing the incidence of dengue in human\npopulations.In this thesis, deterministic mathematical models of human and\nmosquito populations in which either one or two dengue serotypes circulate are\ndeveloped. We adapt these models to enable the investigation of dengue disease\ndynamics in the absence and presence of Wolbachia in order to assess the\nperformance of Wolbachia as a strategy to reduce human dengue incidence. When\nstudying the situation in which a single dengue serotype is present in the\npopulation, we consider scenarios where dengue is introduced into the human\npopulation once and multiple times.\n