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Diagnosis, Differential Diagnosis, and Misdiagnosis of Multiple Sclerosis

2019/06/01 by Andrew Solomon · 1 citation
Medicine · #Multiple Sclerosis Research Studies #Peripheral Neuropathies and Disorders #Medical Case Reports and Studies

paper · doi:10.1212/con.0000000000000728

openalex publication_date 2019/06/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/15

Abstract

PURPOSE OF REVIEW: The diagnosis of multiple sclerosis (MS) is often challenging. This article discusses approaches to the clinical assessment for MS that may improve diagnostic accuracy. RECENT FINDINGS: Contemporary diagnostic criteria for MS continue to evolve, while knowledge about diseases that form the differential diagnosis of MS continues to expand. Recent data concerning causes of MS misdiagnosis (the incorrect assignment of a diagnosis of MS) have further informed approaches to syndromes that may mimic MS and the accurate diagnosis of MS. SUMMARY: This article provides a practical update on MS diagnosis through a discussion of recently revised MS diagnostic criteria, a renewed consideration of MS differential diagnosis, and contemporary data concerning MS misdiagnosis.

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