A Novel Human Polyomavirus Closely Related to the African Green Monkey-Derived Lymphotropic Polyomavirus
2011/02/10 by Nelly Scuda, Jörg Hofmann, Sébastien Calvignac‐Spencer +5 · 13 citations
Engineering · Medicine · #BK virus #Biology #Full-Duplex Wireless Communications #Gene #Genetics #Genome #Kidney #Kidney transplantation #Nested polymerase chain reaction #Parvovirus B19 Infection Studies #Phylogenetic tree #Phylogenetics #Polymerase chain reaction #Polyomavirus Infections #Polyomavirus and related diseases #Virology #Virus
paper · doi:10.1128/jvi.02602-10
openalex publication_date 2011/02/10 · openalex created_date 2025/10/10 · openalex updated_date 2026/06/11
Abstract
We identified a novel human polyomavirus from a kidney transplant patient under immunosuppressive treatment, by use of a generic PCR. The genome of the virus was completely amplified and sequenced. In phylogenetic analyses, it appeared as the closest relative to the African green monkey-derived lymphotropic polyomavirus (LPV). Further investigation of clinical samples from immunocompromised patients with specific nested PCR revealed additional positive samples, indicating that the virus naturally infects humans. The virus was tentatively named human polyomavirus 9 (HPyV9). The previously observed seroreactivity to LPV in human populations might find a partial explanation in the circulation of HPyV9.
Citations
Cited by
- Age-Specific Seroprevalences of Merkel Cell Polyomavirus, Human Polyomaviruses 6, 7, and 9, and Trichodysplasia Spinulosa-Associated Polyomavirus
- Discovery of a Novel Polyomavirus in Acute Diarrheal Samples from Children
- Novel polyomaviruses in shrews (Soricidae) with close similarity to human polyomavirus 12
- Identification of a Novel Human Polyomavirus in Organs of the Gastrointestinal Tract
- Seroepidemiology of Human Polyomaviruses in a US Population
- Different Serologic Behavior of MCPyV, TSPyV, HPyV6, HPyV7 and HPyV9 Polyomaviruses Found on the Skin
- Trichodysplasia spinulosa is characterized by active polyomavirus infection
- Detection of Novel Polyomaviruses, TSPyV, HPyV6, HPyV7, HPyV9 and MWPyV in Feces, Urine, Blood, Respiratory Swabs and Cerebrospinal Fluid
- Seroprevalence rates of HPyV6, HPyV7, TSPyV, HPyV9, MWPyV and KIPyV polyomaviruses among the healthy blood donors
- Seroprevalence of Human Malawi Polyomavirus
- The prevalence of STL polyomavirus in stool samples from Chinese children
- Characterization of the self-assembly of New Jersey polyomavirus VP1 into virus-like particles and the virus seroprevalence in Japan
- Human polyomavirus 9 [wikipedia]
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