2021/03/10 by Sajjad Shirazi, Clark M. Stanford, Lyndon F. Cooper · 2 citations
Dentistry · Medicine · #Dental Research and COVID-19 #SARS-CoV-2 detection and testing #COVID-19 diagnosis using AI
paper · pdf · doi:10.3390/jcm10061158
openalex publication_date 2021/03/10 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/23
Knowledge about the detection potential and detection rates of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in various body fluids and sites is important for dentists since they, directly or indirectly, deal with many of these fluids/sites in their daily practices. In this study, we attempt to review the latest evidence and meta-analysis studies regarding the detection rate of SARS-CoV-2 in different body specimens and sites as well as the characteristics of these sample. The presence/detection of SARS-CoV-2 viral biomolecules (nucleic acid, antigens, antibody) in different clinical specimens depends greatly on the specimen type and timing of collection. These specimens/sites include nasopharynx, oropharynx, nose, saliva, sputum, bronchoalveolar lavage, stool, urine, ocular fluid, serum, plasma and whole blood. The relative detection rate of SARS-CoV-2 viral biomolecules in each of these specimens/sites is reviewed in detail within the text. The infectious potential of these specimens depends mainly on the time of specimen collection and the presence of live replicating viral particles.