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Biosynthesis of bioactive natural products from Basidiomycota

2018/12/13 by Hsiao‐Ching Lin, Ranuka T. Hewage, Yuan‐Chun Lu +1 · 1 citation
Medicine · Biochemistry, Genetics and Molecular Biology · Agricultural and Biological Sciences · #Fungal Biology and Applications #Phytochemical compounds biological activities #Mycorrhizal Fungi and Plant Interactions

paper · doi:10.1039/c8ob02774a

openalex publication_date 2018/12/13 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

The Basidiomycota, also called club fungi, comprise a diverse group of fungi. Basidiomycota are strongly related to ecosystem functioning along with human life. These fungi display a wide range of bioactivities, and some are known to produce of deadly toxins or hallucinogens. Some Basidiomycota have be used as medicinal mushrooms for thousands of years. Recently, the biosyntheses of several classes of natural products from Basidiomycota have been reported. Here, we review recent studies on the biosynthetic pathways and enzymes of bioactive natural products from Basidiomycota fungi, with a focus on terpenoids, alkaloids, ribosomally synthesized and post-translationally modified peptides (RiPPs), and polyketides.

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