2000/03/13 by Bruce Barut, Leonard I. Zon · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · #Bioinformatics #Biology #Computational biology #Danio #Disease #Epigenetics and DNA Methylation #Gene #Genetics #Genetics, Bioinformatics, and Biomedical Research #Genome #Genomics #Human disease #Medicine #Model organism #Pathology #Zebrafish #Zebrafish Biomedical Research Applications
paper · doi:10.1152/physiolgenomics.2000.2.2.49
openalex publication_date 2000/03/13 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/15
Barut, Bruce A., and Leonard I. Zon. Realizing the potential of zebrafish as a model for human disease. Physiol Genomics 2: 49–51, 2000.—The value of the zebrafish ( Danio rerio) as a model for human disease has been substantiated by a number of recently published papers. Several zebrafish mutants with “human” diseases have been found, spanning a variety of human pathologies. These successful studies utilizing the zebrafish have been made possible by the development of key reagents such as YAC, PAC, and BAC libraries, as well as radiation hybrid panels. With the further establishment of new tools and access to the newly generated resources, the zebrafish is poised to serve as a novel model for human disease.