Identification of Genetic Factors that Modify Clinical Onset of Huntington’s Disease

2015/07/01 by Jong‐Min Lee, Jong-Min Lee, Vanessa C. Wheeler +39 · 3 citations
Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · #Age of onset #Allele #Biology #Disease #Fungal and yeast genetics research #Gene #Genetic Neurodegenerative Diseases #Genetic association #Genetics #Genome-wide association study #Genotype #Huntington's disease #Internal medicine #Locus (genetics) #Medicine #Mendelian inheritance #Mitochondrial Function and Pathology #Single-nucleotide polymorphism #Trinucleotide repeat expansion

paper · pdf · doi:10.1016/j.cell.2015.07.003

crossref issued 2015/07/01 · crossref published 2015/07/01 · crossref published-print 2015/07/01 · openalex publication_date 2015/07/01 · crossref created 2015/07/30 · openalex created_date 2016/06/24 · crossref deposited 2019/08/28 · crossref indexed 2026/08/04 · openalex updated_date 2026/08/04

Citations

• Ubiquitin–proteasome system involvement in Huntington’s disease
• Statistical significance for genomewide studies
• Finding the missing heritability of complex diseases
• A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
• 400: A Method for Combining Non-Independent, One-Sided Tests of Significance
• Unified Huntington's disease rating scale: Reliability and consistency

Cited by

• CAG Repeat Not Polyglutamine Length Determines Timing of Huntington’s Disease Onset
• On the wrong DNA track: Molecular mechanisms of repeat-mediated genome instability
• Bernhard Landwehrmeyer [wikipedia]