Potential of Ethenone (Ketene) to Contribute to Electronic Cigarette, or Vaping, Product Use–associated Lung Injury

2020/06/18 by Kathleen R. Attfield, Wenhao Chen, Kristin J. Cummings +5 · 1 citation
Medicine · #Smoking Behavior and Cessation

paper · doi:10.1164/rccm.202003-0654le

openalex publication_date 2020/06/18 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29

Abstract

<p>In 2019, the United States\nexperienced an unprecedented outbreak of electronic cigarette (e-cigarette), or\nvaping, product use– associated lung injury (EVALI). Although reports of\nlipidladen macrophages in BAL fluid raised the possibility that EVALI\nrepresented exogenous lipoid pneumonia, case series that focused on\nhistopathology found patterns of acute lung injury, including diffuse alveolar\ndamage and organizing pneumonia, often with bronchiolitis. Thus, the available evidence to date suggests\nthe outbreak is characterized by an airway-centered chemical pneumonitis rather\nthan acute exogenous lipoid pneumonia.</p>

Cited by

• Ethenone [wikipedia]

Related

• Potential for release of pulmonary toxic ketene from vaping pyrolysis of vitamin E acetate
• Cardiopulmonary Impact of Electronic Cigarettes and Vaping Products: A Scientific Statement From the American Heart Association
• Understanding potential mechanisms of harm: the drivers of electronic cigarette-induced changes in alveolar macrophages, neutrophils, and lung epithelial cells
• The effect of e-cigarette aerosol emissions on respiratory health: a narrative review
• Clinical Presentation and Diagnostic Evaluation of Vaping Related Lung Injury in Youth