Intercalating TOP2 Poisons Attenuate Topoisomerase Action at Higher Concentrations

2019/08/10 by Mandeep Atwal, Rebecca L. Swan, Rebecca Swan +6 · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · Engineering · #Cancer therapeutics and mechanisms #Semiconductor materials and devices #Synthesis and Biological Evaluation

paper · pdf · doi:10.1124/mol.119.117259

openalex publication_date 2019/08/10 · crossref created 2019/08/10 · crossref issued 2019/10/01 · crossref published 2019/10/01 · crossref published-print 2019/10/01 · crossref deposited 2025/02/19 · openalex created_date 2025/10/10 · openalex updated_date 2026/06/24 · crossref indexed 2026/07/20

Citations

• DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs
• Anthracyclines: Molecular Advances and Pharmacologic Developments in Antitumor Activity and Cardiotoxicity
• Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187
• Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer

Cited by

• Topoisomerase inhibitor [wikipedia]