Enantiopure Tetrahydro-β-carbolines via Pictet−Spengler Reactions with N-Sulfinyl Tryptamines

2000/06/01 by Christiaan Gremmen, Bianca Willemse, Martin J. Wanner +1 · 1 citation
Chemistry · #Synthesis and Catalytic Reactions #Asymmetric Synthesis and Catalysis #Advanced Synthetic Organic Chemistry

paper · doi:10.1021/ol006034t

openalex publication_date 2000/06/01 · openalex created_date 2016/06/24 · openalex updated_date 2026/06/26

Abstract

The influence of N-sulfinyl chiral auxiliaries on the stereochemistry of the Pictet-Spengler reaction has been investigated. From enantiopure (R)-N-p-toluenesulfinyltryptamine a new and efficient route to enantiopure tetrahydro-beta-carbolines has been established.

Citations

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