The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

2004/06/20 by Mitsutoshi Yoneyama, Mika Kikuchi, Takashi Natsukawa +6 · 11 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Immune Response and Inflammation #RNA regulation and disease #interferon and immune responses

paper · doi:10.1038/ni1087

crossref issued 2004/06/20 · crossref published 2004/06/20 · crossref published-online 2004/06/20 · openalex publication_date 2004/06/20 · crossref created 2004/06/20 · crossref published-print 2004/07/01 · crossref deposited 2023/05/18 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/05 · crossref indexed 2026/08/05

Citations

• Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA

Cited by

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• Nonself RNA-Sensing Mechanism of RIG-I Helicase and Activation of Antiviral Immune Responses
• 5′-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I
• Antiviral-Activated Dendritic Cells: A Paracrine-Induced Response State
• Genetic Dissection of Interferon-Antagonistic Functions of Rabies Virus Phosphoprotein: Inhibition of Interferon Regulatory Factor 3 Activation Is Important for Pathogenicity
• Rabies Viral Mechanisms to Escape the IFN System: The Viral Protein P Interferes with IRF-3, Stat1, and PML Nuclear Bodies
• Transfection [wikipedia]