2026/01/01 by Nuo Wang, Shoulong Zhang, Jinghua Wang +2
paper · doi:10.4103/ni.ni_1321_21
crossref issued 2026/01/01 · crossref published 2026/01/01 · crossref published-print 2026/01/01 · crossref published-online 2026/02/03 · crossref created 2026/02/03 · crossref deposited 2026/05/14 · crossref indexed 2026/08/05
Abstract: Background and Objective: The aim was to investigate reasons for a pre-hospital delay in patients with acute ischemic stroke (AIS) and patients within the thrombolytic window who did not receive thrombolysis. Subjects and Methods: This study was conducted on AIS patients admitted to the stroke center through interviews and questionnaires. Results: Of the 160 consecutive patients included, 67 (41.9%) arrived at the emergency department (ED) within 4.5 h, and 93 (58.1%) were delayed. The early arrival patients had shorter median onset-to-arrival times ( P n = 9/27.3%) and contradictions ( n = 2/6.1%), the main reasons for pre-hospital delay were patients’ refusal ( n = 12/36.4%) and misdiagnosis on the part of the physician due to atypical symptoms ( n = 4/12.1%). Conclusions: Lack of stroke education, symptom stabilization, and non-emergency medical system utilization were the main reasons for the pre-hospital delay. Patients’ refusal and misdiagnosis were the main reasons of patients who were eligible for thrombolytic treatment but did not finally receive thrombolysis.